Bone Metastases News

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Location of bone metastasis may affect outcomes in metastatic renal cell carcinoma - Healio



Location of bone metastasis may affect outcomes in metastatic renal cell carcinoma 
Healio
Approximately 30% of patients with metastatic renal cell carcinoma have bone metastases, which are associated with considerable morbidity, a high likelihood of skeletal complications and poor prognosis. Five percent of patients with metastatic disease ...

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Zoledronic acid more cost-effective than denosumab for bone metastases - Healio



Zoledronic acid more cost-effective than denosumab for bone metastases 
Healio
Administering generic zoledronic acid every 3 months appeared more cost-effective than monthly denosumab in reducing the risk for skeletal-related events among women with breast cancer and bone metastases, according to a study published in Journal of ...

 


Pain Control More Easily Achieved With Nurse-Led Education in Bone Metastases - Oncology Nurse Advisor



Oncology Nurse Advisor
 
Pain Control More Easily Achieved With Nurse-Led Education in Bone Metastases 
Oncology Nurse Advisor
Patients undergoing radiotherapy (RT) for painful bone metastases achieved better pain control quicker if they also received nurse-led education (NLE) on pain, according to study results presented at the 2017 Palliative and Supportive Care in Oncology ...

 


Bone-Targeted Therapy for Prostate Cancer: Radium-223 - OncLive



OncLive
 
Bone-Targeted Therapy for Prostate Cancer: Radium-223 
OncLive
Joe O'Sullivan, MD, FRCPI, FFRRCSI, FRCR: I'd really like to move the discussion on to bone-targeted therapy for metastatic castration-resistant prostate cancer. Chris, I'll start with you, as an expert in the field and as the leading author of one of ...

 


LDH a Predictor for OS in mCRPC Following Radium-223 - OncLive



OncLive
 
LDH a Predictor for OS in mCRPC Following Radium-223 
OncLive
van der Doelen and his colleagues evaluated men treated for mCRPC in the Netherlands from September 2013, when the use of radium-223 was approved for mCRPC patients with symptomatic bone metastases, through March 2016. Median follow-up until ...

 


Prognostic value of site-specific metastases and therapeutic roles of surgery for patients with metastatic bladder ... - Dove Medical Press



Prognostic value of site-specific metastases and therapeutic roles of surgery for patients with metastatic bladder ... 
Dove Medical Press
Materials and methods: A population-based retrospective study using Surveillance, Epidemiology and End Results dataset was performed and metastatic bladder cancer patients were classified according to the sites of metastases (bone, brain, liver, lung ...

 


Radical Prostatectomy for Patients With Oligometastatic Prostate Cancer - Cancer Network



Radical Prostatectomy for Patients With Oligometastatic Prostate Cancer 
Cancer Network
Conventional imaging with CT and bone scan lacks sensitivity and specificity for detecting small-volume or early metastases. Fortunately, we are in the midst of an imaging revolution in prostate cancer, with the emergence of newer imaging modalities ...

 


First-in-human data validate MRI-linac - Medical Physics Web



Medical Physics Web
 
First-in-human data validate MRI-linac 
Medical Physics Web
The Utrecht team treated four patients with lumbar spinal bone metastases, with a single fraction of 8 Gy prescribed to the target volume while minimizing dose to the spinal cord and the rest of the body. The treatments demonstrated the system's ...

 


PET/CT for Prostate Cancer: From Diagnosis to Metastasis - Renal and Urology News



Renal and Urology News
 
PET/CT for Prostate Cancer: From Diagnosis to Metastasis 
Renal and Urology News
The most studied agent in this setting has been 11C-choline-PET/CT, which showed increased sensitivity for lymph node and bone metastases compared with the standard of care (CT and 99mTc bone scan). A significant limitation of 11C-choline-PET/CT ...

 


Binding molecule could improve injected radiation therapy - Cornell Chronicle



Binding molecule could improve injected radiation therapy 
Cornell Chronicle
But radium-223 targets areas of bone metastasis and is not effectively attached to tumor targeting molecules, which would be needed to treat widespread metastatic cancers. Another radionuclide, actinium-225 (Ac-225), has shown promise in treating ...